The first form factor of the early PC clones was the AT style. This gave birth later to what became known as the “Baby AT” which was a common motherboard type for many years along with the AT type power supply. The original AT motherboard measured 305 x 350 mm. The BabyAT boards varied in size, maximum was 220 x 350 mm. In 1995, Intel introduced the ATX style to replace AT/Baby AT.
Refer to the previous articles showing Compaq low profile desktops to see an example of a proprietary implementation, in this case using a riser card for the slots.
These days low profile clones and some brandnames are produced using MicroATX boards put into a case which has a low profile backplane. A brandname example is the IBM Netvista small form factor desktop PCs in the era of the Celeron 766. A clone case example is the Foxconn DH153 chassis. The case backplane is lower than the standard PCI card and only accepts low profile cards that are fitted with a bracket made in this size. Often, manufacturers produce cards in the low profile form factor and supply brackets for both backplane sizes with the card; however it is necessary to shop around to find them. The Compaq D5S low profile desktop shown in a recent article in this blog was a hybrid; it uses a low profile graphics card in an AGP slot as well as providing two full height PCI slots on a riser. However it’s not clear whether the AGP card was a standard low profile design or a proprietary unit.
The picture below shows an ATX board and micro ATX alongside each other.